ConsumerMed.org

Best Weight Loss Medications in 2025

Below are top-rated online providers for prescription weight loss. Compare options in minutes and choose the one that fits your goals and budget.

Updated

Disclosure: We receive referral fees from the brands listed below. More
Start at $119 with fast shipping
most popular
1
Brand Logo
9.9
Outstanding

Noom GLP1-RX

  • Start at $119, no insurance required to begin
  • Clinician care and coaching included via the GLP-1 Companion
  • Access to GLP-1 meds including Wegovy and Zepbound, if clinically appropriate
    • learn more
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2
Brand Logo
9.7
Excellent

Noom Microdose

  • Plans start at $119, with clinician care and 1:1 coaching included
  • Microdose dosing to reduce side effects - over 70% of members report none
  • 24/7 messaging with clinicians and home delivery available where eligible
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3
Brand Logo
9.6
Excellent

Remedy Meds

  • Quick online eligibility quiz, no insurance required
  • Prescriptions within 24 hours, meds shipped within 48 hours
  • Unlimited virtual provider visits included
  • No contracts, cancel ANYTIME
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4
Brand Logo
9.5
Great

Sesame

  • Start at $99/month, video visit + unlimited messaging included
  • No insurance required to join; insurance accepted for GLP-1 meds; HSA/FSA eligible
  • Prescription access if appropriate, with provider prior-authorization support
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5
Brand Logo
9.4
Good

Ro

  • Start for just $179 with free same-day shipping, no insurance required
  • Same active ingredient as Ozempic®, Wegovy®, Zepbound®
  • Forbes Special: $100 OFF with code Forbes2025
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6
Brand Logo
9.3
Good

Weight Watchers

  • Start for $25 with a 12-month commitment
  • 1:1 clinical care with insurance coordination, dietitians, and unlimited Workshops
  • Access to FDA-approved meds like Wegovy or Zepbound if you qualify
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7
Brand Logo
9.2
Good

MEDVi

  • Start from $179, no insurance required + free shipping
  • Unlimited medical consults and 24/7 support included
  • Weight loss guaranteed or your money back
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8
Brand Logo
9
Good

Sprout

  • 2-min eligibility quiz, no insurance required
  • Flat $249/month, all-inclusive with same price at any dose
  • If approved, prescription in 24 hours and meds ship within 2 business days
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9
Brand Logo
8.9
Good

Eden

  • Quick online eligibility quiz, no insurance required
  • Free expedited shipping and same price at every dose, no hidden fees
  • Doctor-led plans with unlimited check-ins and an active member community
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10
Brand Logo
8.9
Good

Fridays

  • Quick online eligibility quiz, no insurance required
  • Unlimited provider visits, 1-on-1 dietitian support, SESH app included
  • Insurance concierge and prior authorization support for medications
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Our Top Choice

Start at $119 with fast shipping
most popular
1
Brand Logo
9.9
Outstanding

Noom GLP1-RX

  • Start at $119, no insurance required to begin
  • Clinician care and coaching included via the GLP-1 Companion
  • Access to GLP-1 meds including Wegovy and Zepbound, if clinically appropriate
    • learn more
VISIT SITELearn More at Noom GLP1-RX

How to Choose the Best Weight Loss Medication Program

Comprehensive Guide for 2025

Prescription weight loss medications have changed how people approach long-term weight management. Whether you’re exploring your first medically supervised program or looking to switch providers, today’s telehealth platforms offer more options than ever — but knowing where to start can be challenging.

This guide will walk you through the essentials of choosing the right program, from understanding different types of medications to knowing what level of support and monitoring you might need. Our comparisons above highlight the most trusted providers, and here you’ll find expert-backed tips to help you make an informed choice.

Common Prescription Options

Prescription weight loss programs may include:

  • • GLP-1 Medications: Such as semaglutide (Ozempic®, Wegovy®) or tirzepatide (Zepbound®, Mounjaro®), which help regulate appetite and blood sugar.
  • • Non-GLP-1 Options: Including orlistat, phentermine-topiramate, and bupropion-naltrexone, which work in different ways to support weight loss.

Always confirm with a licensed provider which medication is safe and effective for your needs.

What to Look for in a Weight Loss Medication Program

Medical supervision

Look for providers offering ongoing access to licensed clinicians, with regular check-ins and adjustments to your plan.

Lifestyle and Coaching Support

Programs that combine medication with nutrition, exercise, and behavior-change guidance often lead to better long-term results.

Prescription Access & Convenience

Check whether the provider offers home delivery, pharmacy pick-up, or both.

Cost & Insurance Coverage

Prices vary widely — some programs are cash-pay only, while others accept insurance or offer payment plans. Be sure to confirm medication costs, subscription fees, and lab requirements.

Personalization

Some services offer fully customized plans based on lab results and health history, while others use standardized protocols. Decide which approach fits your needs.

Risks & Side Effects

All prescription medications can have side effects, ranging from mild digestive symptoms to more serious risks. A reputable provider will review your health history, monitor your progress, and adjust your plan if needed.

Final Words

Choosing the right weight loss medication program in 2025 means balancing medical safety, personal goals, and program features. Whether you prioritize the newest medications, the most robust coaching support, or the most affordable plan, this guide — along with our detailed comparisons above — will help you make a confident, informed decision.